Phosphodiesterase-5 which are present in Erectile dysfunction
Drugs are produce beneficial results not Just for erectile dysfunction but also for Other parts of body We know that blood flows to all parts of our body.
so PDEF-5 inhibitors are useful in treating many diseases like PDE-5 inhibitors can be effective in treating erectile dysfunction even for many men who also have diabetes, those who are older, and those who have co-existing ischemic heart disease.
The original intention was to develop PDE-5 inhibitors as a treatment for angina (chest pain- that occurs when heart is starved for oxygen)PDE-5 inhibitors actually improve blood flow even in areas where there is a blockage of an artery, thereby having a protective effect on the heart muscle.
"Although the enzyme PDE-5 has been found in tissue and arteries of the brain, Sildenafil does not appearto dilate cerebral arteries or have an effect on cerebral blood flow or blood flow velocity, an indication that there is no increased risk of stroke or hemorrhage.
PDE-5 exists in blood platelets, cells that play a major role in the blood clotting process, but Sildenafil appears to have no direct impact on platelet function.So I think PDEF is really a miracle?? Right
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